Biden receives another negative Covid test after close contact with positive staffer

President Biden on Wednesday tested negative for Covid-19, the White House announced, his second negative PCR test since coming into close contact with a staffer who later tested positive for the virus.

Biden tested negative on a PCR test on Monday, after receiving a negative rapid result on Sunday.

The White House revealed on Monday evening that a mid-level staff member who is “a close contact” of the President tested positive for Covid-19 on Monday morning after spending about 30 minutes “in proximity to the President on Air Force One” on Friday.

The US Centers for Disease Control and Prevention recommends testing five to seven days after close contact with someone with suspected or confirmed Covid-19.

The US Food and Drug Administration on Wednesday authorized the first oral antiviral treatment for Covid-19: Paxlovid, a pill made by Pfizer.

This is the first antiviral Covid-19 pill authorized for ill people to take at home, before they get sick enough to be hospitalized.

Paxlovid combines a new antiviral drug named nirmatrelvir and an older one called ritonavir. 

Last week, Pfizer released updated results that showed the treatment cut the risk of hospitalization or death by 89% if given to high-risk adults within a few days of their first symptoms. If given within the first five days of symptoms, the efficacy was similar: 88%.

Some more background: In November, the Biden administration announced that it would purchase 10 million treatment courses for $5.295 billion. A five-day course of Paxlovid includes three pills given twice a day. President Biden said he was encouraged by the “promising data” from Pfizer and said the drug would “mark a significant step forward in our path out of the pandemic.”

He called Paxlovid a “potentially powerful tool in our fight against the virus, including the Omicron variant,” but stressed that getting vaccinated and receiving a booster shot remained “the most important tools we have to save lives.”

Separately, Merck has requested emergency use authorization for its antiviral pill, molnupiravir. It was narrowly recommended by FDA’s advisers in a 13-10 vote at the end of November after data showed it cut the risk of hospitalization or death by 30% among high-risk adults. This was lower than an earlier analysis suggesting that number could be around 50%. The FDA has not announced whether it will authorize the treatment.

Remdesivir, sold under the brand name Veklury, is the only antiviral approved by FDA for treatment of Covid-19. It’s given intravenously, not as a pill that can be taken at home.

Given the rapid rise of Covid-19 cases across the United States, 2022 will be off to a “much weaker start” than predicted earlier, according to Moody’s Analytics Chief Economist Mark Zandi.

The Delta variant has already impacted the US economy in the summer of 2021, with GDP growth of 2% instead of the earlier predicted 5-6%, Zandi said, adding that he expects Omicron to do as much damage, especially given the example of the variant’s impact in the United Kingdom.

If President Biden’s Build Back Better legislation is entirely shelved, “that’s going to cut at least a half a percentage point off of growth and probably a bit more in calendar year 2022,” Zandi said.

“That’s consequential … The folks getting checks in December aren’t going to get money in January. That’s going to be a hit to the economy right away,” he said Wednesday. “I think at this point we should focus on the growth aspects [of the legislation.] I don’t think inflation is going to be the issue people think it is.”

A total of seven positive Covid-19 cases have been detected aboard the Seven Seas Mariner cruise ship, the Colombia’s Cartagena Department of Health Authority (DADIS) announced Wednesday. 

Among the seven positive cases are six cruise members and one tourist who are in quarantine. It is not clear if the seven Covid-19 cases on the ship are of the Omicron variant.

“Immediately after receiving the information, the cruise operation contingency protocol was activated and determines if the infected will remain isolated in quarantine inside the ship,” reads the press release from DADIS.

All other travelers and crew members on the ship must remain onboard due to the “epidemiological risk” until further notice, DADIS said.

DADIS also stated the outbreak does not create a risk for the city. 

On Monday, the first three cases of the Omicron variant were identified in Colombia according to the country’s National Institute of Health. 

In a video posted on Twitter, Health Minister Fernando Ruiz said that all three cases were travelers coming from the United States and Spain. Two of the cases are in the city of Cartagena and one case is in the city of Santa Marta.

The United Kingdom reported 106,122 Covid-19 cases on Wednesday, crossing the 100,000 threshold for the first time since the pandemic began, according to government figures. 

The UK has seen a 58.9% increase in confirmed cases in the last seven days. 

On Tuesday, British Prime Minister Boris Johnson said there will be no further Covid-19 restrictions brought in for England before Christmas, adding that there is not currently “enough evidence” to justify tougher measures.

He did not rule out bringing in any further measures after Christmas, however, adding “if the situation deteriorates we will be ready to take action if needed.”

CNN’s Livvy Doherty and Lauren Kent contributed reporting to this post. 

The mayor of Miami-Dade announced “new and expanded measures” to address “the very alarming rise in cases” of Covid-19.

Miami-Dade Mayor Daniella Levine Cava told reporters during a press conference Wednesday that the county is expanding testing by extending hours and opening three to five additional sites.

“Over the last several days we’ve seen over 200% increase in the demand for testing across the county,” Levine Cava said, adding the county is testing between 40,000 and 50,000 people a day.

Levine Cava also announced she is reimplementing the indoor mask mandate in county buildings, effective immediately.

Additionally, the mayor said she has requested more monoclonal antibody treatments from the state health department and the federal government. Levine Cava said the county will distribute thousands of at-home testing kits and is laying the groundwork to provide Pfizer’s antiviral pills as soon as they are approved and available.

The mayor said the county will continue measures such as on-site vaccinations for nursing home residents, testing wastewater, and requiring hospitals to report on daily Covid-19 case counts.

Most people who have been vaccinated against Covid-19 experience some side effects, but most are mild or very mild, and serious adverse effects are rare, according to a study published Wednesday in the medical journal JAMA Open Network.

After receiving a second dose of the Pfizer/BioNTech or Moderna vaccine or one dose of the Johnson & Johnson vaccine, about 80% of people reported some side effects – the most common being fatigue, muscle pain, headache and chills. But only 0.2% of people reported experiencing an allergic reaction or anaphylaxis after full vaccination – a total of 27 people out of more than 11,000 responses.

For this study, researchers from the University of California, San Francisco, conducted daily, weekly and monthly surveys about health and Covid-19-related events among an online cohort of adults between March 26 and May 19, 2021. The survey included nearly 20,000 participants, though not all participants responded to all questions. 

The study also found that there was a “strong association” to adverse reactions to the Covid-19 vaccine among those who reported being infected with Covid-19 prior to being vaccinated.

People who received the Moderna vaccine were about twice as likely to report experiencing side effects than those who received the Pfizer/BioNTech vaccine, as were women. Those who received the J&J vaccine had lower odds of adverse effects, along older people and those with asthma.

More on the study: The researchers note that while the surveyed group was diverse, rural residents and people reporting lower subjective social status are underrepresented. Also, not all participants responded to all surveys, which may affect results.

New York Sen. Chuck Schumer, the Senate majority leader, said he’s sending a letter to the Federal Emergency Management Agency (FEMA) requesting 100 more Covid-19 mobile testing sites for New York.

Schumer made the announcement during a Wednesday morning press conference with New York City Mayor Bill de Blasio.

He said that although FEMA has announced that they are sending six additional testing sites, New York needs more.

Rep. Antonio Delgado, a Democrat from New York, announced Wednesday that he has tested positive for Covid-19, one of several members of Congress to announce they are positive in the past several days.

Delgado said he is vaccinated and boosted.

GOP Rep. Nicole Malliotakis of New York tested positive for Covid-19 on Monday, her communications director Natalie Baldassarre tells CNN.

On Sunday, three other Democratic members of Congress announced that they have breakthrough coronavirus infections.

Sens. Elizabeth Warren of Massachusetts and Cory Booker of New Jersey as well as Rep. Jason Crow of Colorado shared that they had tested positive for Covid-19 via tweets from their official accounts.

The House and Senate are not in session at this moment.

See Rep. Delgado’s full statement:

CNN’s Greg Clary and Annie Grayer contributed reporting to this post.